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Immunopathogenesis of IBD: current state of the art

However, most experts agree that this is well below the physiological needs of most individuals

Favia et al., Pharmacological targets of metabolism in disease: opportunities from macrophages

As for the best treatment duration, in an open-label trial GlyNAC supplementation for 16-weeks or 24-weeks resulted in similar outcomes, while withdrawing GlyNAC for 12-weeks led to loss/decrease of benefits