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Single-cell analysis of anti-BCMA CAR t cell therapy in patients with central nervous system autoimmunity

Bolivar, AM, Duzagac, F, Deng, N, Reyes-Uribe, L, Chang, K, Wu, W, Bowen, CM, Taggart, MW, Thirumurthi, S, Lynch, PM, You, YN, Rodriguez-Pascual, J, Lipkin, SM, Kopetz, S , Scheet, PA, Lizee, GA, Reuben, A, Sinha, K, Vilar Sanchez, E

Gigascience 9 , giaa094 (2020)

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Metformin at a concentration of 0.05 mM inhibits NOX and suppresses the palmitate-induced elevation of ER stress markers and ROS levels in a AMPK-independent manner, whereas 0.5 mM metformin inhibits ROCK activity and activates AMPK