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Second, the functional significance of mtDNA methylation remains to be fully defined: whether it primarily modulates mitochondrial gene expression or acts predominantly as a protective mechanism against ROS-induced damage through altered DNA packaging and TFAM binding is still under active investigation

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Homocysteine and reclassification of cardiovascular disease risk

Prospective evaluation of alcohol abuse and alcoholic liver injury in men as predictors of development of cirrhosis

This is because the gut microbiota convertes BBR into absorbable dihydroBBR (dhBBR) and increases the intestinal absorption rate (Zhao et al., 2021a