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There is one important protection worth noting: "If you are not a candidate or approved for GLP-1 medication, your subscription will be cancelled, and we will work with you to find another solution." The company also states elsewhere that "if not deemed appropriate, you will be immediately refunded." The practical takeaway: the billing structure is quarterly, cancellation is available but fees already paid are described as non-refundable, and there is a minimum commitment period described in the terms

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LDN has a stimulatory effect on immune cells via an indirect interaction with their opiate receptors, whereas high-dose naltrexone has an inhibitory effect