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Oxidation at SOX2s Cys265 site disrupted its activity, sensitizing cells to lipid peroxidation and ferroptosis (Wang et al

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DFO reduces the symptoms of RIRI and has been used clinically to treat iron overload disorders, and electroretinography (ERG) and visual evoked potentials (VEP) tests have been performed to confirm that retinal visual function improves in subjects after DFO treatment (274)

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