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Discovered in 2015 by researcher Changhan David Lee and colleagues at the University of Southern California, MOTS-c sits at the intersection of some of the most active areas in longevity science: mitochondrial biology, insulin sensitivity, skeletal muscle metabolism, and the molecular response to exercise

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Transcytosis at the bloodbrain barrier

The EVOKE Trial Results The EVOKE (NCT04777396) and EVOKE+ (NCT04777409) trials enrolled 3,808 adults aged 55-85 with mild cognitive impairment or mild dementia due to Alzheimers disease

The lack of robust BPC-157 human trialsspecifically Phase II and Phase III studiesmeans that definitive conclusions about its efficacy, optimal dosing, and long-term safety in humans cannot be made