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Vitamin K deficiency significantly accelerates bone loss progression (91)

The following figure illustrates how the state of iron metabolism influences distinct cellular fates ( Figure 3 )

Glaser, R

NETosis is induced dependent on ROS, which majorly originates from nicotinamide adenine dinucleotide phosphate oxidases, whose activation is dependent on an elevation in cytoplasmic Ca 2+ concentration and occasionally on ROS generation in the mitochondria (144)