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Copperdoped polydopamine nanoparticlesmediated GSH/GPX4depleted ferroptosis and cuproptosis sensitizes lung tumor to checkpoint blockade immunotherapy

moreover, many studies may focus on the short-term effects of antioxidants, while the long-term impact on CAP outcomes and overall health may not be well-documented and also the quality of the studies included in the review may vary, with some studies having methodological limitations such as lack of randomization, blinding, or control groups, which can affect the reliability of the results

These results indicate that treatment with GABA, DSIP-CBBBP and more effectively reduced wakefulness time, with DSIP-CBBBP showing the most substantial reduction, suggesting its potential as a therapeutic agent for mitigating insomnia