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29 Progressively several other nanomedicines were reported as potential candidates for RA therapy like MTX combined with nanoemulsions, 30 siRNA-loaded chitosan nanoparticles, 31 curcumin-loaded carboxy methyl cellulose acetate (CMCAB), 32 exosomes as biomimetic particles, 33 stimuli-responsive liposomes, 34 MTX and siRNA loaded carbon nanotubes, 35 poly(amidoamine) (PAMAM) dendrimers functionalized with chondroitin sulphate and with anti-TNF- to provide anti-inflammatory properties 36 and mesoporous silica nanoparticles encapsulating dexamethasone 37 to deliver the traditional drugs

Then, six sections were obtained for each guinea pig tissue and placed onto positively charged slides

APR-246, also known as PRIMA-1MET, is a promising new therapeutic agent that targets TP53 mutated cancers

10.3390/ijms252212177 53 CimminoG.De NiscoM.AlonsoC.GravinaC.PiscopoV.LemosR.et al (2024)

Suppression of apoptosis proteins (IAPs) regulates caspase activity