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So it takes us back in history, but there was a period between World War II and 1970s where there was a lot of motivation in the research community to do these grand randomized controlled trials of nutrition

134,135 Bao et al

Medication is the core method of conservative treatment, primarily including analgesics (such as non-steroidal anti-inflammatory drugs and opioid analgesics), muscle relaxants, corticosteroids, and so on ( The limitations of current options, ranging from traditional conservative methods to surgical interventions, have led researchers to seek new therapeutic alternatives (Xing et al., 2021)

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