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These advantages are derived from combinatorial actions enhancing brain antioxidant capacity while concurrently lowering cardiometabolic risk factors such as insulin resistance, obesity, and hypertension (Ellouze et al., 2023)

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[72] co-cultured ADMSCs with degenerative NP cells, and explored the involved signalling pathways and regulatory networks through the lncRNA and mRNA expression profiles in the system

Reviewer #3 (Remarks to the Author) This manuscript tackles an important aspect of debilitating diseases such as newborn brain injury and multiple sclerosis, that of identifying therapeutic agents which promote remyelination in injury

Discussion Our results provide evidence that intrastromal implantation of a cell-free bioengineered collagen-based material can be a safe and feasible means to reverse the pathologic corneal thinning and deformation in advanced keratoconus