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Description

Osborn et al., 2016)

Jakhotia, S

Expert Opinion on Therapeutic Targets

Structural analysis of BsGGT and BlGGT demonstrated that their binding pocket is solvent exposed, as they lack lid loop or any of that sort to cover the active site

In preclinical work it up- and down-regulates a large number of genes tied to matrix production, remodeling, and antioxidant defense, and it ferries copper a cofactor for lysyl oxidase and superoxide dismutase into tissue