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Isoelectric focusing : Higher pI due to charge elimination

doi:10.3390/molecules28207165

Weinreb et al., 2018) considering the large sample size needed for deriving statistically and clinically meaningful results from the small effect size, the high cost of the studies, the potential patient dropout or loss of adherence, and the compromise in drawing robust conclusions from incomplete data (McGhee et al., 2016

Moreover, Con A-injected mice also showed low GSH/GSSG ratio, increased hydrogen peroxide and high MDA level in the liver and spleen compared with Con A-injected WT mice (Figure 6)