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faecalis was observed to secrete heat-resistant proteases GelE and SerEin by relying on the Fsr quorum-sensing system to inhibit the hyphae morphogenesis of C

This inhibition is crucial as it reduces the activation of Notch3s intracellular domain (NICD), leading to decreased Notch3-mediated signaling pathways that are typically involved in glioma cell survival and proliferation