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Gene expression changes also involved pathways linked to autoimmune diseases, cancer, and major depressive disorder, indicating that even brief circadian disruption can trigger systemic inflammatory responses with potential long-term health consequences 146

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Abstract BACKGROUND: Glucagon-like peptide-1 receptor agonists and their analogues have emerged as effective pharmacotherapies for obesity

Statistical analysis Statistical analysis was performed using IBM SPSS Statistics version 27.0, and graphing was conducted using GraphPad Prism version 10.2.2