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In laboratory research, glutathione is extensively studied for its roles in phase II xenobiotic metabolism, where it conjugates with reactive electrophiles via glutathione S-transferase enzymes

These findings may reflect an immediate stress response following ECT [38], as electrophysiological intervention might temporarily promote the conversion of GSH to GSSG [39]

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1 Oxidation-driven storage lesion and its post-transfusion impact 1.1 Oxidative stress as a driver of storage lesions in red blood cells During their hypothermic storage, red blood cells (RBCs) accumulate a wide array of defects, collectively known as storage lesion