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Glutathione helps neutralize free radicals , supports liver detoxification , enhances immune cell function , and protects cellular DNA from oxidative damage

importantly, these trends parallel alkyl carboxylate substrate specificity 23,40

The released inhibitor not only inhibited the influx of pyruvate into the mitochondria but also effectively blocked the tricarboxylic acid (TCA) cycle, which is fueled by glucose and lactate, thereby disrupting aerobic respiration and alleviating tumor hypoxia (Figure 6B)