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The Q-SYMBIO study, a randomised controlled trial with 420 participants, demonstrated that CoQ10 supplementation (100 mg three times daily) reduced cardiovascular mortality in patients with moderate to severe heart failure

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*Correspondence: Jianqun Lin [email protected] Pang [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

If hypermethylation occurs, a higher than normal level of these methyl groups are attached to the DNA, which can lead to changes in how genes are turned on or off