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Yet, individual responses to supplements may differ

The cerebral cortex exhibited numerous darkly stained degenerated neurons, irregular pyramidal cells with pyknotic and hyperchromatic nuclei, and extensive vacuolation of the neuropil

Decreased expression of the GABAA receptor in fragile X syndrome

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Future clinical trials are urgently needed to determine optimal dosage regimens, establish dose-response relationships, and assess the long-term safety of EC supplementation