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Description

Preclinical and clinical studies have demonstrated that bioactive compounds such as polyphenols, alkaloids, terpenoids, saponins, and flavonoids exert beneficial effects on AD-related pathways by reducing oxidative stress, suppressing neuroinflammation, preventing A aggregation, and modulating tau hyperphosphorylation (Liu et al., 2024)

319 (7202): 1046 Greene DA, Arezzo JC, Brown MB, et al

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What is Reduced Glutathione

Thereafter, it participates in the integrative stress response (ISR) and activates the transcription factor ATF4, which initiates the corresponding gene expression program