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GPX4, a key enzyme that protects against lipid peroxidation and a central regulator of ferroptosis, was significantly reduced in SH-SY5Y-APP Swe/Ind cells and further decreased upon BSO treatment (Figure 3D and Supplementary Figure 2A and F)

Furthermore, Xiong et al

FIGURE 25-4: Conversion of propionyl-CoA to succinyl-CoA

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