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Redox Signaling 2009, 11, 15471558

Peptides trigger the production of IGF-1, VEGF, FGF, and KGF, all of which promote stem cell activation, dermal papilla proliferation and follicle regeneration

J Intern Med 282:284297

In the context of the IGF-1 LR3 pathway, this suggests that while extended IGF-1 activity can still support muscle repair and regeneration, the overall responsiveness of tissues to these signals may be somewhat reduced compared to higher-producing genotypes