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As well as the above, the clinical trial improved the ability of NK cells to kill their target two-fold, demonstrating a reduction in oxidative stress as well

This paper shows that three cytoplasmic thiol-disulphide oxidoreductases (E10R, A2.5L and G4L) encoded by vaccinia virus cooperate in a cytosolic pathway for the formation of disulphide bonds in virion proteins

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This aligns with previous research indicating that aging is associated with decreased levels of BDNF, catalase, and cyclic GMP