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One is a tetrahedral geometry with three nitrogen atoms and one oxygen atom from three histidine ligands, imitating the active site of CA, and the other is a distorted trigonal bipyramidal geometry also coordinated by the histidine ligands

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G protein-coupled receptor (GPCR) is a 7-transmembrane protein receptor containing a G protein-binding region in the cytoplasm and a ligand-binding region outside the cell

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