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DFO reduced chronic inflammation and symptoms of autoimmune diseases in animal studies (Di Paola et al., 2022)

After 1 week of STZ administration animals having random serum glucose more than 240 mg/dl were considered as diabetic

The apparent promise of Ebselen in reducing SOD1 accumulation in vivo hints at the therapeutic potential of modulating posttranslational modification of SOD1 protein to counteract SOD1 misfolding, suggesting a greater research focus be paid towards developing similar treatment strategies