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When deciding on antineoplastic combination therapy for persistent/resistant glioblastoma, we recommend analyzing the long-term hormetic and chronic effects on cross-resistance and multi-drug resistance in primary cell cultures from patients

This further leads to the reversal of mitochondrial dysfunction, thereby increasing mitochondrial -oxidation and reducing intracellular oxidative stress to prevent hepatic lipotoxicity (53, 54)

The pivotal trial enrolled 404 HIV-infected patients with excess abdominal fat accumulation