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BMC Plant Biol 22(1):496 Rushton DL, Tripathi P, Rabara RC, Lin J, Ringler P, Boken AK, Langum TJ, Smidt L, Boomsma DD, Emme NJ, Chen X (2012) WRKY transcription factors: key components in abscisic acid signalling

It has also been shown to lower homocysteine levels, a molecule linked to inflammation and cognitive decline, with longitudinal studies linking optimal B12 levels with improved cognitive function, mood and reduced risk of neurodegenerative disease

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These findings highlight TNF-s central role in the pathogenesis of both type 2 and type 1 diabetes, particularly through inflammation and immune-mediated mechanisms, and suggest potential therapeutic avenues for further research

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