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Second generation corticosteroids Beclomethasone diproprionate and slow release budesonide are second generation corticosteroids with a high affinity for the intracellular glucocorticoid receptor in the GI tract, exerting local and selective, potent anti-inflammatory effects at the site of inflammation[33]

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The anti-cancer effect of coumarin-based agents like coumarin-triazole, coumarin-chalcone, coumarin-thiosemicarbazone derivatives, coumarin-metal complexes, furanocoumarin, pyranocoumarin, pyrone-substituted coumarin, and their derivatives have been found more potent than that of simple coumarin

Zhang Y, et al

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