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Start by reviewing relevant literature for in vitro and in vivo concentration ranges and design small pilot studies to determine tolerability and preliminary efficacy for your specific model

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Given the clinicopathological significance of SLC1A5 201 and the observation that the level of the SLC1A5 variant is negatively correlated with prognosis in several cancer types 16 , targeting the SLC1A5 variant is a promising strategy to starve cancer cells and induce antitumor effects