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This heightens womens susceptibility to neuronal damage, leading to a higher (than men) incidence of AD as they age

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J Endocrinol 166 : 579590 Coschigano KT et al

However, problems such as maintenance of their immunoregulatory function and longevity of the cells are needed to be considered

[151] combined IVC at 1.5 g/kg once daily for three consecutive days with mFOLFOX6 or FOLFIRI with or without bevacizumab in a 14 day cycle in advanced colorectal and gastric cancer patients (treatment was continued for 12 cycles, disease progression, unmanageable toxic effects, or withdrawal of consent)