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The sequence for the IL-12 mRNA encoded for both of its subunits joined by a linker to enable cytokine production via a single transcript

Neuropeptides 55, 99109

By enabling precise genetic modifications, CRISPR offers the potential to correct or suppress genes implicated in pathological responses to IRI, such as oxidative damage, inflammation, apoptosis, and mitochondrial dysfunction [91]

For example, hexokinase, G6PD, aldose reductase, and Na + /K + ATPase showed decreased activity of up to 57% compared to the control lenses, although UV-B exposure did not result in cataract formation (169)

doi: 10.1016/j.bpj.2020.10.020 72 WolfKte LindertMKrauseMAlexanderSte RietJWillisALet al