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the dose range of 2 to 20 mg / kg body weight is generally recommended, whereby the exact dose depends on the individual circumstances in the context of the disease

It is a molecule naturally produced by the human body, and decades of clinical use across both topical and injectable applications have not identified significant adverse effects

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Further, CYP2E1-induced cytotoxicity sensitizes the hepatocytes against TGF-beta 1 [128]

Integration of metabolic imaging with other biomarkers and clinical parameters could enable precision metabolic medicine in NSCLC [83, 84]