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Biopsy showed that the apoptosis of a diabetic heart was 85 times higher than that of the nondiabetic heart, indicating that cardiomyocytes in diabetes were sensitive to suffer CD (e.g

Exosomes from human induced pluripotent stem cells derived mesenchymal stem cells improved myocardial injury caused by severe acute pancreatitis through activating Akt/Nrf2/HO-1 axis

In mouse models of diseases such as ALI, liver fibrosis, NAFLD, and NASH, treatment with lipophilic antioxidants was shown to prevent disease progression and extend life expectancy

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Glutathione - Synthesis SFRBM Education Program Dickinson et al.13 de novo synthesis - 7 Glycine -glutamylcysteinylglycine -glutamylcysteine (GSH) GSH synthase ATP ADP Glutathione - Synthesis SFRBM Education Program Dickinson et al.14 Glutathione breakdown 1 The linkage of glutamate to cysteine via the gamma carbon makes GSH refractory to standard proteases