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Cognitive function in obese individuals improves substantially with weight loss alone, but the direct central GLP-1R effects may contribute additional benefit beyond what weight reduction alone would predict

For example, lipid droplet accumulation in cancer cells has been shown to inactivate immune signaling molecules and foster a hospitable environment for cancer cell progression (144)

Strategic timing may enhance the peptide's effectiveness

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doi: 10.1161/01.ATV.0000163846.51473.09