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Sikiric et al., 2020b) than the generally established angiogenic growth factors, epidermal growth factor (EGF), basic fibroblast growth factor (bFGF), and vascular endothelial growth factor (VEGF) (Tarnawski and Ahluwalia, 2012

The honest summary is that long-term human safety data is missing and the angiogenesis mechanism is an unresolved theoretical concern

This is an uncommon side effect that may only occur with corticosteroids and not with a pure anesthetic medication

Is it symptom-modifying, or is it truly disease modifying