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Omega-3 fatty acid supplementation in severe brain trauma: case for a large multicenter trial

In imiquimod-induced mouse models, betulin-loaded NLCs produced marked lesion improvement accompanied by reductions in systemic inflammatory cytokines such as TNF-, IL-6, and IL-17, along with a lowered spleen index, indicating that their therapeutic benefit extends beyond local skin improvement to systemic immunomodulation [123, 124]

(2010) Enhanced infection of liver sinusoidal endothelial cells in a mouse model of antibody-induced severe dengue disease Cell Host Microbe 7, 128139 29

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