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In comparison to monocyte-derived macrophages from healthy volunteers, macrophages from patients with active CD were more susceptible to ferroptosis induced by in vitro exposure to H 2 O 2

Furthermore, whether Exos regulate other molecules implicated in GSH synthesis or iron metabolism to affect ferroptosis remains an open question

Carbon-centered lipid radicals (R ) rapidly react in oxygenated tissues with the molecular oxygen-forming lipid peroxyl radicals (ROO) according to the reaction (Valko et al

Finally, patients who already have intestinal barrier damage need to receive specific medical treatment and to promote recovery and prevent further complications under the close supervision of a medical professional

TM5441, a plasminogen activator inhibitor-1 inhibitor, protects against high fat diet-induced non-alcoholic fatty liver disease