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In two separate case reports, one newborn (2 months old) with early infantile Leigh-like SLC19A3 gene defect (129) and one (30 days old) with THTR2 deficiency (130) responded dramatically differently to thiamine supplementation

Consult your GP to assess whether symptoms are genuinely related to the supplement and discuss alternative formulations if needed

Post-acute ischemic stroke hyperglycemia can aggravate the disruption of the BBB and reduce the overall energy metabolism level of cerebral microvascular ECs by inhibiting mitochondrial transfer (Xu et al., 2024)

Everything has improved me, especially with the pain I had with my knees

[DOI] [PubMed] [Google Scholar] 45.Beilharz EJ, Russo VC, Butler G, Baker NL, Connor B, Sirimanne ES, Dragunow M, Werther GA, Gluckman PD, Williams CE, and Scheepens A