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Abstract 180 , 75th Annual Meeting of the Endocrine Society (1993)

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Gain insights into the potential therapeutic applications of 5-Amino 1MQ for conditions like insulin resistance, heart disease, and more

As fat tissue grows and more NNMT is produced, higher amounts of hormones and pro-inflammatory signals are produced that are responsible for weight gain and other chronic diseases such as type 2 diabetes and cardiovascular disease. NNMT is responsible for converting nicotinamide (NA) into 1-methylnicotinamide (1-MNA), which takes it out of the NAD salvage pathway (see the diagram below)