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Fu R, Sun F, Wang W, et al

Enhanced risk of thrombotic disease in patients with acquired vitamin B12 and/or folate deficiency: role of hyperhomocysteinemia

Biomed Pap 160(4):461466

XDH is a homodimer of approximately 300 kDa, with four redox centers in each subunit: a molybdenum cofactor (Mo-co), two iron-sulfur (Fe-S) centers, and a flavin adenine dinucleotide (FAD) domain (51)

For patients in the validation cohort, the 5-year OS rates were 77.0%, 62.5% and 45.4% in the low, intermediate, and high-risk groups, respectively (p 2.87 cells/mm 2 (HR=3.762, p=0.000009)) and proportion of M-MDSCs of total cells ( 3 cm) or located in an area that is difficult to ablate, combined radiofrequency ablation (RFA) and transarterial chemoembolization (TACE) (TACE+RFA) is the standard locoregional therapy