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Stewart LE, Sophie JK, Arabella S, Elizabeth JE, Bruce JT, John T

Conversely, CPP-CAND targets FOXO4, which is explicitly expressed in senescent cells, providing a senescent cell-specific target

Comparison to Other Senolytic Therapies To contextualise FOXO4-DRI, lets compare it to other senolytic approaches or peptides you may be aware of (helpful given your clinics peptide focus)

Seal the vial and place it on an orbital mixer, shaking for 24 hours to reach equilibrium in thermodynamic experiments or for 1 hour in kinetic experiments