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8e), despite the accumulation of intracellular 5FU and continued TS inhibition

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For the observation of mitochondria generating ROS, the cells were incubated with HBSS (Sigma-Aldrich) containing 5 M MitoSOX for 10 min at 37 C in the dark and were then washed with PBS 3 times to remove any residual dye

Endometrial cancer Endometrial cancer (EC) ranks among the most common gynecological malignancies in women worldwide, with rising incidence rates attributed to factors such as obesity, sedentary lifestyles and aging populations [66]