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of Industrial Engineering, Tsinghua Univ., Beijing, China Objective : 30 years ago the WHO published criteria for the diagnosis of postmenopausal osteoporosis

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489 LncRNA HOTAIR also exerts a pivotal influence in DNA damage repair by promoting recruitment of EZH2 to the MYC promoter and upregulating the transcription of DDR molecules such as KU70, KU80, DNA-PKs, and ATM, which increases DNA repair in breast cancer and leads to radioresistance