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It's worth noting that the expression and activity of DAO can be influenced by genetic factors, lifestyle, and diet

World J Gastroenterol 2013, 19 (18), 27612771

Semin Reprod Med (2015) 33:2705

A.WangY.-Tet al

Despite promising results, challenges such as off-target toxicity, poor cell membrane permeability and poor bioavailability, remain obstacles to clinical translation of conventional STING agonists