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10.1016/j.spinee.2012.12.005 103 HuangZ.ChengX.ZhaoJ.LiuZ.WangJ.FengX.et al (2019)

Burning feet syndrome formally called Grierson-Gopalan syndrome after the physicians who first described it refers to a constellation of symptoms: persistent burning, heat, and sometimes tingling or aching in the feet, characteristically worse at night and partially relieved by cool surfaces or cold water

Mild redness or bruising at the injection site

Preferentially frequent blood sampling every 30 to 60 minutes from six hours prior to and one hour following habitual bedtime is collected to assess the individuals dim light melatonin onset (DLMO) and circadian phase

Some evidence suggests that persistently elevated plasma vitamin B12 concentrations may be associated with cancer, although more research is needed to confirm this (Urbanski et al., 2020