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We have an ongoing investigation of dementia in people with Parkinson disease

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doi: 10.1056/NEJMoa1613683 73 GalskyMDSaciASzaboPMHanGCGrossfeldGColletteSet al

BALB/c mice subcutaneously inoculated with A549 cells, oral gavage of 40 mg/kg lovastatin combined with intraperitoneal administration of 200 g per dose of PD-L1 antibody resulted in downregulation of GPX4 expression and increased lipid peroxidation levels in the tumor tissue

To further explore whether MB regulates additional ECM components besides elastin, we screened ECM genes using the Bio-Rad PCR array, which contains 30 genes known to be involved in human ECM remodeling