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doi: 10.3390/cells11233756 40 NsiahN

Trends Biosci

Further evidence for the involvement of miRNAs in the mechanism of ECT comes from a study involving 64 patients with TRD: At baseline, expression of miRNA-223-3p was significantly lower in responders compared to non-responders and demonstrated moderate predictive capacity for ECT response (AUC = 0.76, 95% CI = 0.60.91) [28]

10.3389/fimmu.2020.00230 312

However, many challenges remain in the current research on nanoparticle delivery systems to alleviate radiation-induced inflammation and injury, especially in terms of unsatisfactory biocompatibility, low drug delivery rates, and lack of long-term stability