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Approval status (read carefully): elamipretide received FDA accelerated approval in September 2025 under the brand Forzinity but only for Barth syndrome (to improve muscle strength in patients weighing 30 kg), on a surrogate endpoint, with a confirmatory trial potentially required [3]

Increased bleeding Any surgery involves a certain amount of bleeding

In the studies we have, its safety signal has been very reassuring, but that's different from FDA approval

Larazotide is a peptide designed to tighten these loose junctions and help close the gaps in the gut lining

The result is controlled, localised, and short-term loss of sensation without affecting mental alertness.