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CTGF enhances resistance to 5-FU-mediating cell apoptosis through FAK/MEK/ERK signal pathway in colorectal cancer

doi: 10.2217/nnm-2019-0323

In parallel, SHMT2 interacts with -catenin in the cytoplasm to prevent its ubiquitin-mediated degradation, thereby activating the Wnt/-catenin signaling pathway