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96 Specifically, this compound decreases the levels of GSH and superoxide dismutase (SOD), increases malondialdehyde (MDA) levels, promotes E-cadherin expression, and lowers N-cadherin expression, 96 indicating that gambogenic acid can induce ferroptosis to inhibit TGF-1-induced EMT by disrupting the oxidative stress balance of melanocytes

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The biggest difference found in protein expression in depressive brains was in the proteins involved in energy metabolism.[ref] Researchers cant look at mitochondrial function inside the brains of living people very easily

doi: 10.3390/nu11122941

10.3724/zdxbyxb-2022-0456 J Zhejiang Univ (Med Sci)